Abstract: [Objective] The Qimantag region of Qinghai Province is located at the southern edge of the Qaidam Basin and is an important part of the East Kunlun metallogenic belt. It is characterized by widely developed Late Paleozoic-Mesozoic magmatism and abundant polymetallic deposits of iron, copper, cobalt, lead, zinc. The Yemaquan iron polymetallic deposit is a typical representative of skarn-type mineralization in the Qimantag area. A large number of studies have been carried out on the Mesozoic granite-silicate rock-forming mineralization. However, it is not clear whether there are multiple periods of magmatism and mineralization in the Yemaquan. [Methods] This study is based on detailed field geological surveys. It employs petrographic observations, zircon and garnet LA-ICP-MS U-Pb dating, whole-rock major and trace element analysis, and zircon Hf isotope testing to uncover the presence of two episodes of magmatic intrusion and mineralization at the Yemaquan iron polymetallic deposit. [Results] The zircon ages of multiple intrusive rocks at the southwest surface of the mining area are concentrated around 224 Ma, consistent with the hydrothermal muscovite Ar-Ar ages reported in previous studies. This indicates the presence of Late Triassic magmatism and mineralization in the mining area. In the M13 anomaly zone in the southeast, the zircon ages of granodiorite at the deep part of the drill hole are 395 Ma, which is approximately the same as the