Abstract: Abstract：[Objective] The Zhenghe area is a gold polymetallic ore-concentrated area in Fujian province along the southeast coast of China. However, due to the complicated geological settings and low research level, the characteristics of mineralization and alteration remain unclear. [Methods] This paper takes the Yanpitou polymetallic exploration area (located in the northwest side of the Dongkeng volcanic basin) as the research object, and makes the detailed field geological survey, drill hole mineralization-alteration zoning, and quantitative analysis for alteration, which provide efficient information of alteration and geochemistry of country rock for further deeper exploration. [Results] The results indicate that the Yanpitou area is characterized by Pb-Zn mineralization and Cu-Mo mineralization. The zoning of mineralization can be divided into: potassium rock zone, skarn zone, metallic mineralized zone, mica schist zone, and hornfels zone. From the potassic to skarnized, elements such as Si, Al, TFe (total iron), Ca, and K, exhibit a state of depletion; from the skarnized, hornfels to mineralized zone, the majority of elements migrate towards the mineralized zone, indicating the ore-forming fluids are active during mineralization. It is suggested that: the alteration types are closely associated with mineralization in the Yanpitou polymetallic exploration area, which are potassic and skarn, and the mica schist zone is also related to mineralization. [Conclusions] In addition, based on the previous research, the mineralization-alteration zoning model for the Yanpitou polymetallic exploration area has been established. It is concluded the survey potential for deep exploration, and the next step in exploration should continue towards the Huangshegang area to the northwest side in the Yanpitou area, where extensive skarn within the Tieshan complex.